I am on record here as being permissive on drugtaking, but also on record as advocating caution where powerful mind-altering substances are concerned.
Here is a hideous case in point. We will be going to a memorial for a friend - more a friend of Herself really - in a few days' time, a charming, kind and very nice person who died in December. Some twenty years ago or more, a man unknown to him walked up behind him and bashed his head in with a ball-peen hammer. Needless to say he was never quite the same again, but courageously resumed his life.
The geezer was promptly caught. He was out of his head on LSD when he did the deed, and claimed in his defence that he thought our buddy was 'the devil'. Stupid, violent and superstitious: not the sort of person who should smoke dope, let alone drop acid. He did a short prison sentence and was then released into the community (instead of being chucked into Broadmoor for the rest of his life). I don't know or care what happened to him after that, but I do hope the fuzz and shrinks are keeping an eye on him. Squalid filthy little swine.
Yes, powerful psychedelics really are a bit risky. Even if you know what you're doing you may forget under the influence. When you take it you can definitely feel idiocy pulling at you.
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Dangers of recreational drugs 