If you are going to be travelling overnight to arrive at 0730 I would tend to favour M5 /M4/M25/M23 to Brighton junction then along A27 .
It may not be the prettiest but probably the fastest route.
The trouble with using A27 after M27 southern route is that Chichester to Brighton is a nightmare of roundabouts and congestion.
Coming back then the A27 up to A272 is indeed a very pleasant drive if you are not in any hurry , Petworth,Midhurst,Winchester etc but if you are driving a large van you are likely to find a build up of very frustrated car drivers behind you...
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