Have rarely seen stunning results from Capsaicin 0.025% and 0.075% creams though I suspect few people use it as recommended (very sparingly 4 times daily) despite my encouragement.
Couple of relative successes with post-herpetic neuralgia (persistent pain after shingles in the elderly).
Chronic pain treatment is a dissapointing subset of GP workload - for every success there's several "you'll need to come to terms with it".
The population is littered with chronic users of opiates like codeine and tramadol with limited long-term benefit, and significant long-term detriment.
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Knees 
Knees 